No Rest for the Wicked is a single-player third-person action RPG with isometric camera placement.

The game takes place in a medieval game world. The player controls a warrior who travels to a remote island to investigate the cause of a mysterious disease.

The protagonist has a wide range of weapons and armor at his disposal. The combat system is interesting and complex. The chosen weapons and armor have a great impact on the way you fight. The resources collected in the game world can be used to make and improve equipment and other items.